| Primary Identifier | MGI:3775951 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Ldlr |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| description | Insertion of the expression cassette into the 3' untranslated region results in a duplication of exon 13 through part of exon 18. |
| molecularNote | A cassette containing an IRES, human AFP and polyadenylation signal was inserted into the 3' untranslated region along with a floxed neo cassette and resulted in a duplication of exon 13 through part of exon 18. The neo cassette was removed by transient cre expression. Expression of AFP was confirmed by a quantitative immunoassay. |
