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Allele : Gja1<tm8Kwi> gap junction protein, alpha 1; targeted mutation 8, Klaus Willecke

Primary Identifier  MGI:3776013 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Gja1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  The endogenous locus was replaced with a cassette that contained a 5' loxP site, a copy of the endogenous locus, an frt-flanked neo cassette with a 3' loxP site, an open reading frame with an amino acid substitution that resulted in an amino acid substitution of arginine for glycine at position 138 (G138R) and an IRES-eGFP. Only cre-mediated recombinaton can remove the wild-type locus and result in expression of the locus with the nucleotide substitution.
  • mutations:
  • Nucleotide substitutions,
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gja1<flox(G138R)>,
  • Cx43<floxG138R>,
  • Gja1<flox(G138R)>,
  • Cx43<floxG138R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele