| Primary Identifier | MGI:3778383 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Foxp2 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 17 was replaced with an exon 17 that contained a nucleotide substitution resulting in an amino acid substitution of histidine for arginine at position 552 (R552H). A floxed neo cassette was inserted downstream of exon 17 but was removed by transient cre expression. This mutation corresponds to human mutation R553H of FOXP2 that results in speech-language disorders. |
