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Allele : Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Klaus Rajewsky
Primary Identifier  MGI:3778920 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, No functional change, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing the chicken beta actin promoter CAG driving the expression of a floxed neo-STOP cassette followed by cDNA encoding human MIRN 17, 18a, 19a, 20a, 19b and 92 plus an frt-flanked IRES-EGFP cassette and a poly-adenylation site were inserted into the ROSA locus. This allele is also a knockin allele that allows for expression of the human MIRNs contained within it following the cre-mediated removal of the neo-STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • miR-17-92<TG>,
  • Gt(ROSA)26Sor<tm3(CAG-MIRN17-92,-EGFP)Rsky>,
  • miRNA-17-92<OE>,
  • R26<LSL-miR17-92>,
  • miRNA-17-92<OE>,
  • Gt(ROSA)26Sor<tm3Rsky>,
  • R26<LSL-miR17-92>,
  • miR-17-92<TG>,
  • Gt(ROSA)26Sor<tm3Rsky>,
  • Gt(ROSA)26Sor<tm3(CAG-MIRN17-92,-EGFP)Rsky>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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