Primary Identifier | MGI:3777465 | Allele Type | Chemically induced (ENU) |
Gene | Mycbp2 | Inheritance Mode | Recessive |
Strain of Origin | (BALB/c x C57BL/6)F1 X DBA/2J | Is Recombinase | false |
Is Wild Type | false |
description | ENU exposed DBA/2J males were mated with (BALB/c x C57BL/6)F1 females carrying the Tg(Isl1-EGFP*)1Slp reporter. |
molecularNote | ENU mutagenesis induced a A to G transition in exon 65 that generated a new splice donor. This mutation led to an altered mRNA transcript in which a 32 base deletion from exon 65 created a frame shift and a premature termination codon in exon 66. |