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Allele : Ret<tm1Heno> ret proto-oncogene; targeted mutation 1, Hideki Enomoto

Primary Identifier  MGI:3777553 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ret
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A bovine tau-targeted LacZ cassette and a floxed neo cassette were inserted into the first exon deleting 39 base pairs including the start methionine codon and codons for 6 amino acids of the signal peptide. Germ-line, cre-mediated recombination was used to remove the neo cassette. Expression of lacZ was confirmed by beta-galactosidase assay. This is a null allele due to the insertion site.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ret<TLZ>,
  • Ret<TLZ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele