Primary Identifier | MGI:3777553 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Ret |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A bovine tau-targeted LacZ cassette and a floxed neo cassette were inserted into the first exon deleting 39 base pairs including the start methionine codon and codons for 6 amino acids of the signal peptide. Germ-line, cre-mediated recombination was used to remove the neo cassette. Expression of lacZ was confirmed by beta-galactosidase assay. This is a null allele due to the insertion site. |