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Allele : Ret<tm2(RET)Heno> ret proto-oncogene; targeted mutation 2, Hideki Enomoto
Primary Identifier  MGI:3777555 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ret
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed human RET cDNA with an SV40 intron and poly-adenyation site followed by CFP with a poly-adenylation site and an frt-flanked neo cassette were inserted into exon 1 removing 39 base pairs including the start methionine codon and codons for the first 6 amino acids of the signal peptide. Germ-line, flp-mediated recombination was used to remove the neo cassette and leave a floxed RET and a CFP cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ret<f(CFP)>,
  • Ret<fCFP>,
  • Ret<flox>,
  • Ret<flox>,
  • Ret<f(CFP)>,
  • Ret<fCFP>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

22 Publication categories

Trail: Allele




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