| Primary Identifier | MGI:3783297 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(PRNP)650Insra |
| Strain of Origin | 129S7/SvEvBrd | Is Recombinase | false |
| Is Wild Type | false |
| description | This transgene was injected into 129S7/SvEvBrd cells containing Prnptm1Cwe. |
| molecularNote | This transgene contains a human PAC with 110 kb long fragment with the entire human PRNP gene and flanking genes (such as DOPPLE). Three lines were created with 1, 3 and 5 copies of the PAC at one integration site. Line 650 contains 5 copies. Expression in the brain is 6-fold higher than in the null background. |
