Primary Identifier | MGI:3784516 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Nes-cre/ERT2)1Jf |
Strain of Origin | CBA x C57BL/6 | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The enhancer from the second intron of rat Nestin in conjunction with the Hspa1b minimal promoter was used to drive neural stem and progenitor cell-specific expression of a cre/ESR1 (CRE-ERT2) fusion. Cre expression is tamoxifen-inducible. Eleven founder lines were created and one was analyzed (line numbers not specified). |