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Allele : Tg(Ckm-LPL)1Rze transgene insertion 1, Rudolf Zechner

Primary Identifier  MGI:3789040 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ckm-LPL)1Rze
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Mouse Ckm promoter was used to drive skeletal and cardiac muscle-specific expression of human LPL with a G to A transition at position 721 that results in an amino acid substitution of aspartic acid to asparagine at position 156 (D156N). This mutation results in an enzymatically inactive protein. Two lines were created (lines 1 and 2).
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele