Primary Identifier | MGI:3790081 | Allele Type | Targeted |
Gene | Tagln | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The cDNA for bovine PRKG1 isoform beta was inserted immediately downstream of the start methionine followed by a neo cassette. The insertion results in the mutation of glycine 2 of the bovine cDNA to an arginine. Expression of the bovine protein in smooth muscle cells was confirmed by western blot analysis. |