| Primary Identifier | MGI:3795209 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(GPD1)A1Bir |
| Strain of Origin | (C57BL/6J x LT/Sv)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene comprises 12.3 kb of human genomic DNA containing the GPD1 gene, consisting of 3.5 kb of 5' flanking sequence, the 7.6 kb protein-coding region and 1.2 kb of 3' flanking DNA. The 5' flanking sequence includes the proximal and distal promoter regions. Founder line A1 has approximately 6 copies of the transgene. Mice exhibit a much higher level of transgene expression in the cerebral cortex than is normal for the endogenous gene. |
