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Allele : Abcc12<tm1Bor> ATP-binding cassette, sub-family C member 12; targeted mutation 1, Piet Borst

Primary Identifier  MGI:3794121 Allele Type  Targeted
Gene  Abcc12 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  An oligonucleotide targeting strategy was used to introduce a frame-shift and consequently a premature stop codon in the open reading frame by the insertion of 4 bp into exon 2 (the first coding exon) between codons 13 and 14. This allele produces a truncated protein that lacks the amino terminal segment (31 amino acids) due to the presence of an alternative in-frame initiation codon 19 codons downstream.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele