Primary Identifier | MGI:3796426 | Allele Type | Chemically induced (ENU) |
Gene | Suz12 | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This mutation was identified by ENU mutagenesis screen performed with Mpltm1Wsa homozygous mice to identify mutations that suppress thrombocytopenia and/or stem cell defects. A single base pair deletion disrupting the splice acceptor site upstream of exon 16 causes aberrant transcription resulting in reduced protein products. |