Primary Identifier | MGI:3798958 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dgcr2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1 and 2 of the Hprt gene along with a 3' loxP site and neo cassette were inserted into the coding region to create the starting point of a 1.3 Mb genomic deletion as a model for a 1.5 Mb hemizygous deletion in certain 22q11-deletion syndrome patients. |