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Allele : Mecp2<tm1Pplt> methyl CpG binding protein 2; targeted mutation 1, Patrick P L Tam

Primary Identifier  MGI:3800596 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mecp2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 2 kb segment containing exon 3 through the first 170 bp of exon 4 and encoding the methyl-CpG-binding domain was replaced with a floxed neo cassette. The neo cassette was removed by germ line, cre-mediated recombination. The absence of protein product was confirmed by western blot analysis in brain and lung extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mecp2<tm1neoTam>,
  • Mecp2<tm1neoTam>,
  • Mecp2<tm1Tam>,
  • Mecp2<tm1Tam>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele