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Allele : Rnf8<Gt(RRR260)Byg> ring finger protein 8; gene trap RRR260, BayGenomics

Primary Identifier  MGI:3800229 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Rnf8
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap vector is inserted after exon 4, disrupting proper transcription of the gene and generating a fusion product of beta-geo and the N-terminal part of the encoded protein without its C-terminal RING domain which is critical for function. The absence of protein expression was confirmed by western blot analysis on thymocyte extracts.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • RNF8<->,
  • RNF8<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

21 Publication categories

Trail: Allele