|  Help  |  About  |  Contact Us

Allele : Zap70<m6Hefl> zeta-chain (TCR) associated protein kinase; mutation 6, Heinrich Flaswinkel

Primary Identifier  MGI:3800788 Allele Type  Chemically induced (ENU)
Attribute String  Hypomorph Gene  Zap70
Inheritance Mode  Recessive Strain of Origin  C3HeB/FeJ
Is Recombinase  false Is Wild Type  false
molecularNote  ENU mutagenesis induced a transition of A to G leading to an amino acid substitution of glycine for glutamic acid at position 589 (E589G) in the kinase domain. Reduced protein expression was confirmed by western blot analysis on CD4+CD8+ thymocytes. This is a hypomorphic allele.
  • mutations:
  • Single point mutation
  • synonyms:
  • TUM079,
  • Zap70<deltaT3>,
  • TUM079,
  • Zap70<deltaT3>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele