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Allele : Fasl<del1Hong> Fas ligand; deletion 1, Wanjin Hong

Primary Identifier  MGI:3803664 Allele Type  Spontaneous
Gene  Fasl Inheritance Mode  Recessive
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A spontaneous mutation results in the small deletion of 5 nucleotides at the 5' end of the first intron, removing the invariant GT dinucleotide in the 5' splice consensus sequence. Splicing between the first and second exons is aberrant, generating non-functional polypeptides and creating a loss-of-function allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • FasL<del>,
  • FasL<del>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele