Primary Identifier | MGI:3807544 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Nr2e1-cre/ERT2)1Gsc |
Strain of Origin | Not Specified | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | This transgene consists of modified BAC containing the entire coding region of the Nr2e1 gene including flanking regulatory sequences 104 kb upstream and 30 kb downstream, and drives expression of a tamoxifen-inducible form of cre recombinase fusion protein which replaces part of exon 1 of the Nr2e1 gene. 6 lines were generated of which 3 lines are further analyzed. All three lines showed tamoxifen-inducible Cre activity in the developing forebrain. This is a representative record for all 3 lines. |