Primary Identifier | MGI:1857598 | Allele Type | Radiation induced |
Gene | Cryge | Inheritance Mode | Dominant |
Strain of Origin | (102/El x C3H/El)F1 | Is Recombinase | false |
Is Wild Type | false |
description | With the discovery that the mutation is a nucleotide substitution, it has been suggested that CrygeCat2-t may have possibly been spontaneous instead of X-ray induced J:50319. Phenotypic Similarity to Human Syndrome: Dominant Cataracts in heterozygous and homozygous mice mice (J:9528) |
molecularNote | A C to G transversion at nucleotide position 432 in exon 3 of Cryge that creates a premature termination signal and results in a truncated protein after amino acid 143. |