| First Author | Eckler MJ | Year | 2015 |
| Journal | Neuron | Volume | 86 |
| Issue | 4 | Pages | 1100-1108 |
| PubMed ID | 25996137 | Mgi Jnum | J:223289 |
| Mgi Id | MGI:5648638 | Doi | 10.1016/j.neuron.2015.04.020 |
| Citation | Eckler MJ, et al. (2015) Cux2-positive radial glial cells generate diverse subtypes of neocortical projection neurons and macroglia. Neuron 86(4):1100-8 |
| abstractText | We recently published genetic lineage-tracing experiments using the Fezf2 and Cux2 loci. These experiments demonstrated that at both the clonal and population levels Fezf2(+) RGCs are multipotent and that at the population level Cux2(+) RGCs are multipotent. Here, we extend our work on the lineages of Fezf2(+) and Cux2(+) RGCs. Clonal analysis of E10.5 neocortical progenitors suggests that most, if not all, Cux2(+) and Fezf2(+) RGCs generate diverse projection neuron subtypes located throughout layers 2-6. These results support our previous conclusion that both Fezf2(+) and Cux2(+) RGCs are multipotent neocortical progenitors. This Matters Arising Response paper addresses the Gil-Sanz et al. (2015) Matters Arising paper, published concurrently in Neuron. |
