First Author | Muthusamy N | Year | 2018 |
Journal | Sci Rep | Volume | 8 |
Issue | 1 | Pages | 1766 |
PubMed ID | 29379049 | Mgi Jnum | J:260182 |
Mgi Id | MGI:6148407 | Doi | 10.1038/s41598-018-19913-x |
Citation | Muthusamy N, et al. (2018) Foxj1 expressing ependymal cells do not contribute new cells to sites of injury or stroke in the mouse forebrain. Sci Rep 8(1):1766 |
abstractText | The stem cell source of neural and glial progenitors in the periventricular regions of the adult forebrain has remained uncertain and controversial. Using a cell specific genetic approach we rule out Foxj1+ ependymal cells as stem cells participating in neurogenesis and gliogenesis in response to acute injury or stroke in the mouse forebrain. Non stem- and progenitor-like responses of Foxj1+ ependymal cells to injury and stroke remain to be defined and investigated. |