Primary Identifier | MGI:3809545 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(RCAN1)M9Mapr |
Strain of Origin | C57BL/6 x CBA | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A modified human RCAN1 cDNA containing 4kb of upstream sequence, exon 1, exons 5-7, and the 3'-UTR was constructed. Five transgenic founders were produced. Transgenic mice express about 4 times as much protein as wild-type controls. Results reported are primarily for line M9 although M1 is reported to give similar results. |