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Allele : Ano1<tm1Bdh> anoctamin 1, calcium activated chloride channel; targeted mutation 1, Brian D Harfe

Primary Identifier  MGI:3809591 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ano1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 12 was replaced with a neo cassette. This deletion results in a frame shift and a premature stop codon 40 amino acids downstream of the deletion. Seven of the eight transmembrane domains are disrupted due to this frame shift.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • TMEM16A<->,
  • Tmem16a<tm1Bdh>,
  • Ano1<tm1Jrr>,
  • TMEM16A<->,
  • Tmem16a<tm1Bdh>,
  • Ano1<tm1Jrr>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

24 Publication categories

Trail: Allele