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Allele : Myd88<tm1Defr> myeloid differentiation primary response gene 88; targeted mutation 1, Anthony L DeFranco

Primary Identifier  MGI:3809600 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Myd88
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was flanked by loxP sites by placing a FRT-flanked neo-cassette with a 3' loxP site upstream of exon 3 with an additional loxP site being placed downstream of exon 3. Founders were crossed with ACTB-FLPe mice to remove the neo selection cassette. Expression levels of Myd88 were unaffected by loxP insertion. Cre-recombination is predicted to excise exon 3 and create a null allele.
  • mutations:
  • Insertion
  • synonyms:
  • Myd88<fl>,
  • Myd88<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

0 Driven By

172 Publication categories

Trail: Allele