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Allele : Selplg<tm2Rpmc> selectin, platelet (p-selectin) ligand; targeted mutation 2, Rodger P McEver

Primary Identifier  MGI:3809664 Allele Type  Targeted
Attribute String  Null/knockout Gene  Selplg
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The entire 67 residue cytoplasmic domain was deleted except for the membrane proximal arginine. A codon for a second adjacent arginine followed by two stop codons was inserted. A loxed neo cassette was introduced downstream of exon 2 and sebsequently removed by transient cre expression from properly targeted ES cells. The extracellular domain and the transmembrane domain are expressed normally.
  • mutations:
  • Insertion
  • synonyms:
  • deltaCD,
  • deltaCD
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele