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Allele : Il17rb<tm1Bud> interleukin 17 receptor B; targeted mutation 1, Alison L Budelsky

Primary Identifier  MGI:3809835 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il17rb
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was constructed to replace the region of exon 3 that encodes amino acids 38 through 73 with a neomycin selection cassette. Correct targeting was confirmed by Southern blotting. Cultured splenocytes failed to produce IL-5 or IL-13 when incubated with the ligand to the gene product.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IL-17RB,
  • IL-17RB
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele