| Primary Identifier | MGI:3811714 | Allele Type | Targeted |
| Attribute String | Dominant negative, Humanized sequence | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked neomycin resistance gene cassette was inserted into intron 6 and exon 7 was replaced with one in which nucleotide substitutions (CGA-to-TCT) resulted in an amino acid substitution of arginine with serine at position 246 (p.R246S). Transient cre expression was used to remove the neo cassette. |
