| Primary Identifier | MGI:3813569 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sync |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| description | This targeted mutation was created in "E129/sv" ES cells. |
| molecularNote | A loxP site and an frt flanked neomycin selection cassette were inserted in intron 1 and a second loxP site was placed in intron 2. Chimeric mice were bred to a proprietary CMV-cre mouse line on a C57BL/6 background developed by GenOway. This resulted in the excision of both the neomycin selection cassette and exon 2. No protein was detectable immunologically in tissues. |
