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Allele : Tab1<tm1Mis> TGF-beta activated kinase 1/MAP3K7 binding protein 1; targeted mutation 1, Yuji Mishina

Primary Identifier  MGI:3814196 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Tab1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  An frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 9 and an additional loxP site was inserted downtream of exon 10. Germ line, flp mediated recombination was used to remove the neo cassette leaving exons 9 and 10 floxed. This allele is hypomorphic as confirmed by phenotypic observations and western blot analysis on E16.5 brain extracts and newborn keratinocytes.
  • mutations:
  • Insertion
  • synonyms:
  • Tab1<fx>,
  • Tab1<fx>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele