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Allele : Sptlc1<tm1Jia> serine palmitoyltransferase, long chain base subunit 1; targeted mutation 1, Xian-cheng Jiang
Primary Identifier  MGI:3815115 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sptlc1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 7 and 8 were replaced with a neomycin resistance gene. Southern blotting confirmed correct targeting of ES cells. Immunoblot analysis on heterozygote liver extracts indicated protein expression was reduced by half, confirming gene inactivation.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • LCB1<->,
  • LCB1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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