Primary Identifier | MGI:3814224 | Allele Type | QTL |
Gene | Ildr2 | Strain of Origin | DBA/2J |
Is Recombinase | false | Is Wild Type | false |
description | Dbsm1 was identified in obese F2 male animals homozygous for Lepob. |
molecularNote | This allele confers decreased beta-cell mass, impaired glucose tolerance, increased fasting blood glucose levels and decreased blood insulin in obese Lepob males on a CHOW diet compared to C57BL/6J. This allele confers increased blood glucose levels in lean males on a 13 week high fat diet compared to C57BL/J. This allele differs from Ildr2 |