|  Help  |  About  |  Contact Us

Allele : Ildr2<Dbsm1-DBA/2J> immunoglobulin-like domain containing receptor 2; DBA/2J

Primary Identifier  MGI:3814224 Allele Type  QTL
Gene  Ildr2 Strain of Origin  DBA/2J
Is Recombinase  false Is Wild Type  false
description  Dbsm1 was identified in obese F2 male animals homozygous for Lepob.
molecularNote  This allele confers decreased beta-cell mass, impaired glucose tolerance, increased fasting blood glucose levels and decreased blood insulin in obese Lepob males on a CHOW diet compared to C57BL/6J. This allele confers increased blood glucose levels in lean males on a 13 week high fat diet compared to C57BL/J. This allele differs from Ildr2 by the presence of valine rather than alanine at amino acid residue 647 and the presence of alanine rather than threonine at amino acid residue 587.
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele