|  Help  |  About  |  Contact Us

Allele : Tg(Ins-Igf2)1Fbos transgene insertion 1, Fatima Bosch

Primary Identifier  MGI:3818739 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ins-Igf2)1Fbos
Strain of Origin  C57BL/6 x SJL Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Calcific Aortic Valve Disease J:227165 in mice homozygous for Apobtm2Sgy and Ldlrtm1Her and carrying the Tg(Ins-Igf2)1Fbos transgene.
molecularNote  The rat promoter was used to drive islet-specific expression of the mouse gene. Three lines were created (lines 1, 2 and 3) with similar phenotype. Line 1 was chosen as the representative line and has 40 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • RIPI/IGF-II,
  • RIPI/IGF-II
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories

Trail: Allele