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Allele : Uqcrfs1<tm1Ctm> ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1; targeted mutation 1, Carlos T Moraes

Primary Identifier  MGI:3819772 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Uqcrfs1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Mitochondrial Complex III Deficiency in homozygous mice carrying Tg(Camk2a-cre)#Szi (J:188773)
molecularNote  The exon 2 was flanked by loxP sites and a neomycin/thymidine kinase cassette was inserted in the 3' untranslated region via homologous recombination. Western blot analysis detected decreased protein levels in skin but not muscle, heart, brain or liver from homozygotes.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele