| Primary Identifier | MGI:3819793 | Allele Type | Chemically induced (ENU) |
| Gene | Sox4 | Inheritance Mode | Semidominant |
| Strain of Origin | mixed | Is Recombinase | false |
| Is Wild Type | false |
| description | This allele was induced by ENU treatment of a male mouse homozygous for Foxq1sa on a mixed genetic background (mostly 101 and C3H, but derived from a linkage testing stock also homozygous for Wnt3avt (origin: C57BR) and Bloc1s5mu (origin: t-allele stock)). |
| molecularNote | This mutation was identified in an ENU mutagenesis screen focused on the Del(13)39H deletion interval. A T-to-C transition at nucleotide 869 (RefSeq accession no. NM_009238) generates a Ser70Pro missense mutation. This transition introduces a proline residue into the first alpha-helix of the HMG box of the protein product. Allelic complementation suggests this is a functionally null allele. |
