Primary Identifier | MGI:3821930 | Allele Type | Targeted |
Attribute String | Conditional ready, Humanized sequence, Inducible, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | Not Specified |
Induced With | tamoxifen | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A fused human MYC and ESR1 (ERT2) sequence, preceded by a floxed neo cassette with a triple polyadenylation sequence and followed by an IRES-EGFP, was inserted into the ROSA locus. Expression of the fusion product can only be achieved through cre mediated removal of the neo cassette along with its polyadenlylation sequences. |