| Primary Identifier | MGI:3821617 | Allele Type | Targeted |
| Attribute String | Conditional ready, Hypomorph | Gene | Zbtb7b |
| Transmission | Germline | Strain of Origin | B6(Cg)-Tyr<c-2J>/J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding sequence of this gene locus is contained within exons 2 and 3. A loxP-flanked neomycin resistance cassette was placed upstream of exon 2 and an additional loxP site was placed downstream of exon 3. The presence of the neomycin resistance cassette created a hypomorph allele where protein expression was reduced by 80% in CD4+ T cells from mice compound heterozygote for this allele and a null allele. |
