Primary Identifier | MGI:3820649 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-Nfatct1*)1Grc |
Strain of Origin | (C57BL/6J x CBA/J)F1 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The CMV promoter fused to a tetracycline responsive element was used to drive tetracycline-regulated and ubiquitous expression of a modified Nfatc1 gene that encodes a nuclear-localized protein as a result of nucleotide substitutions that encode alanines instead of the serines normally dephosphorylated by calcineurin. No line information is given. |