| Primary Identifier | MGI:3827095 | Allele Type | Chemically induced (ENU) |
| Gene | Scn8a | Inheritance Mode | Semidominant |
| Strain of Origin | BALB/cAnN | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Harwell ENU Mutagenesis |
| molecularNote | This mutation was identified in a hearing screen of C3H/HeH-backcross progeny of an ENU mutagenized (BALB/cAnN x C3H/HeH)F1 mouse and was shown by microsatellite analysis to reside on the BALB/cAnN chromosome. It has been identified as an adenine to thymine transversion at nucleotide position 2942, in exon 17, that results in replacement by valine of a highly conserved aspartic acid at amino acid position 981 (D981V), six amino acids carboxy-terminal of the sixth transmembrane segment of the second domain (D2S6). |
