Primary Identifier | MGI:3829071 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Hras |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A G12D mutation was introduced to the targeted gene along with a reverse orientation lox-stop/puromycin resistance-lox cassette placed in intron 1. The G12D mutant form of protein is conditionally expressed from this gene when a floxed stop segment is excised by Cre. |