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Allele : Lrp1<tm3Ajmr> low density lipoprotein receptor-related protein 1; targeted mutation 3, Anton J M Roebroek

Primary Identifier  MGI:3830332 Allele Type  Targeted
Attribute String  RMCE-ready Gene  Lrp1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Recombination-mediated cassette exchange (RMCE) was used to replace exons 76 through 89 with an frt-flanked cassette containing a cDNA for exons 76 through 89 and a floxed neo gene. The cDNA contains mutations in exon 88 that result in amino acid substitutions of RHRR with AATA and disrupt the NPXY1 site.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • n1,
  • n1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele