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Allele : Bub1<tm1.1Tvd> BUB1, mitotic checkpoint serine/threonine kinase; targeted mutation 1.1, Terry Van Dyke

Primary Identifier  MGI:3830859 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bub1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Germ line, cre-mediated recombination was used to remove the exons 2 and 3 as well as the neo cassette. Removal of these exons results in a frameshift in exon 4 and a premature termination codon in exon 6. The absence of full-length protein product and the presence of a truncated one was confirmed by western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bub1<delta2-3>,
  • Bub1<delta2-3>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele