| Primary Identifier | MGI:3830652 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Gzmb-cre/ERT2)1Dtf |
| Strain of Origin | Not Specified | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A BAC transgenic mouse was created by using a 155 kb fragment of murine chromosome 14 that had been modified by replacing the start codon of the granzyme B gene with the tamoxifen-dependent recombinase Cre/ERT2 gene. Successful integration of the construct was confirmed through genomic PCR. After crossing to a cre reporter strain and administrating tamoxifen, cre expression was detected in activated CD8 T cells and in NK cells. |
