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Allele : Tg(Thy1-MAPT*K369I)K3Gotz transgene insertion K3, Jurgen Gotz

Primary Identifier  MGI:3833383 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1-MAPT*K369I)K3Gotz
Strain of Origin  (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The promoter was used to drive neuron-specific expression of a mutated human cDNA lacking exon 3, containing four microtubule binding domains, and nucleotide substitutions that result in an amino acid substitution of isoleucine for lysine at position 369 (K369). One line was created (K3).
  • mutations:
  • Insertion
  • synonyms:
  • K3,
  • K3
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele