|  Help  |  About  |  Contact Us

Allele : Pold1<tm1Uchi> polymerase (DNA directed), delta 1, catalytic subunit; targeted mutation 1, Arikuni Uchimura

Primary Identifier  MGI:3833573 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Pold1
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  An A to C transversion in exon 10 causes an aspartic acid to alanine amino acid residue change at codon 400. A floxed fragment containing the SV40 splice/polyadenylation signal as well as a neomycin resistance cassette was inserted in intron 10. Western blot analysis of extracts prepared from E12.5 heterozygous whole embryos confirmed that protein product was reduced by about half.
  • mutations:
  • Insertion
  • synonyms:
  • Pold1<->,
  • Pold1<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele