|  Help  |  About  |  Contact Us

Allele : Pak1<tm1Cher> p21 (RAC1) activated kinase 1; targeted mutation 1, Jonathan Chernoff

Primary Identifier  MGI:3834675 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pak1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector replaced the coding sequence of the p21-binding domain and the inhibitory domain with a neomycin resistance gene in the anti-sense orientation. A lack of protein was confirmed in homozygote bone marrow-derived mast cells by immunoblot assays.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

35 Publication categories

Trail: Allele