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Allele : Gli2<tm1Blnw> GLI-Kruppel family member GLI2; targeted mutation 1, Baolin Wang

Primary Identifier  MGI:3834146 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Gli2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin cassette was inserted upstream of the last exon, part of which was replaced with corresponding mouse cDNA sequences containing Ser-Ala mutations in the codons for the first four protein kinase A sites (S789A, S805A, S817A and S848A). The neomycin was left in place because of the increased lethality of heterozygotes that occured when it was removed.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Glir<P1-4>,
  • Glir<P1-4>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele