|  Help  |  About  |  Contact Us

Allele : Tg(tetO-PIK3CA*H1047R)13Lca transgene insertion 13, Lewis C Cantley

Primary Identifier  MGI:3834439 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-PIK3CA*H1047R)13Lca
Strain of Origin  FVB/N Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The tetracyclin operator was used to drive expression of the human cDNA with a point mutation that results in the amino acid substitution of arginine for histidine at position 1047 (H1047R). Three lines were generated (13, 121 and 3011). Line 13 carries around 20 copies of the transgene compared to around 60 in line 121.
  • mutations:
  • Insertion
  • synonyms:
  • p110-alpha H1047R,
  • p110-alpha H1047R
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele