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Allele : Tg(TcraTcrbAD10)1Hed transgene insertion 1, Stephen M Hedrick

Primary Identifier  MGI:3835444 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TcraTcrbAD10)1Hed
Strain of Origin  (C57BL/6 x SJL)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Productively rearranged Tcra and Tcrb genes were cloned from the murine T cell clone AD10 that is specific for pigeon cytochrome-c. In mice expressing I-Ek, or I-Eb, greater than 90% of thymocytes and T cells express the transgenic TCR. The alpha-chain of this transgenic TCR differs by one amino acid (a threonine instead of an alanine at position 99) to the alpha chain of the transgenic TCR expressed in Tg(TcrAND)53Hed transgenic mice.
  • mutations:
  • Insertion
  • synonyms:
  • AD10,
  • AD10
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories

Trail: Allele